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Combined 18 F-FDG PET-CT and DCE-MRI to Assess Inflammation and Microvascularization in Atherosclerotic Plaques
Author(s) -
Martine T.B. Truijman,
Robert M. Kwee,
Raf H.M. van Hoof,
Evelien Hermeling,
Robert J. van Oostenbrugge,
Werner H. Mess,
Walter H. Backes,
Mat J.A.P. Daemen,
Jan Bucerius,
Joachim E. Wildberger,
M. Eline Kooi
Publication year - 2013
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.113.003140
Subject(s) - medicine , positron emission tomography , nuclear medicine , neovascularization , stenosis , rank correlation , magnetic resonance imaging , standardized uptake value , correlation , radiology , inflammation , positron emission , stroke (engine) , fluorodeoxyglucose , angiogenesis , mechanical engineering , geometry , mathematics , engineering , machine learning , computer science
Hallmarks of vulnerable atherosclerotic plaques are inflammation that can be assessed with 18fluorine-fluorodeoxyglucose positron emission tomography/computed tomography, and increased neovascularization that can be evaluated by dynamic contrast-enhanced-MRI. It remains unclear whether these parameters are correlated or represent independent imaging parameters. This study determines whether there is a correlation between inflammation and neovascularization in atherosclerotic carotid plaques.

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