Rivaroxaban for Stroke Prevention in East Asian Patients From the ROCKET AF Trial
Author(s) -
Ka Sing Wong,
Dai Yi Hu,
Abraham Oomman,
Ru San Tan,
Manesh R. Patel,
Daniel E. Singer,
Günter Breithardt,
Kenneth W. Mahaffey,
Richard C. Becker,
Robert M. Califf,
Keith A.A. Fox,
Scott D. Berkowitz,
Werner Hacke,
Graeme J. Hankey
Publication year - 2014
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.113.002968
Subject(s) - medicine , rivaroxaban , stroke (engine) , clinical trial , physical therapy , atrial fibrillation , warfarin , mechanical engineering , engineering
In Rivaroxaban Once Daily Oral Direct Factor Xa Inhibitor Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF) trial, rivaroxaban was noninferior to dose-adjusted warfarin in preventing stroke or systemic embolism among patients with nonvalvular atrial fibrillation at moderate to high stroke risk. Because of differences in patient demographics, epidemiology, and stroke risk management in East Asia, outcomes and relative effects of rivaroxaban versus warfarin were assessed to determine consistency among East Asians versus other ROCKET AF participants.
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