Does Sex Influence the Response to Intravenous Thrombolysis in Ischemic Stroke? | Zendy

Svetlana Lorenzano | Zendy; Niaz Ahmed | Zendy; Anne Falcou | Zendy; Robert Mikulík | Zendy; Turgut Tatlisumak | Zendy; Christine Roffe | Zendy; Nils Wahlgren | Zendy; Danilo Toni | Zendy

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Does Sex Influence the Response to Intravenous Thrombolysis in Ischemic Stroke?

Author(s) -

Svetlana Lorenzano,

Niaz Ahmed,

Anne Falcou,

Robert Mikulík,

Turgut Tatlisumak,

Christine Roffe,

Nils Wahlgren,

Danilo Toni

Publication year - 2013

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.113.002908

Subject(s) - medicine , thrombolysis , odds ratio , intracerebral hemorrhage , confidence interval , modified rankin scale , stroke (engine) , confounding , fibrinolytic agent , tissue plasminogen activator , surgery , ischemic stroke , subarachnoid hemorrhage , ischemia , myocardial infarction , mechanical engineering , engineering

Women are more likely to have a worse outcome after an acute stroke than men. Some studies have suggested that women also benefit less from intravenous thrombolysis after an acute ischemic stroke, but others found no sex differences in safety and efficacy. We aimed to evaluate differences in 3-month outcome between sexes in intravenous tissue-type plasminogen activator-treated patients registered in the Safe Implementation of Treatments in Stroke-International Stroke Thrombolysis Register.

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