Letter by Kawada Regarding Article, “Dabigatran Versus Warfarin: Effects on Ischemic and Hemorrhagic Strokes and Bleeding in Asians and Non-Asians With Atrial Fibrillation” | Zendy

Tomoyuki Kawada | Zendy

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Letter by Kawada Regarding Article, “Dabigatran Versus Warfarin: Effects on Ischemic and Hemorrhagic Strokes and Bleeding in Asians and Non-Asians With Atrial Fibrillation”

Author(s) -

Tomoyuki Kawada

Publication year - 2013

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.113.002844

Subject(s) - medicine , dabigatran , atrial fibrillation , warfarin , hazard ratio , stroke (engine) , confidence interval , major bleeding , cardiology , mechanical engineering , engineering

Hori et al1 conducted a randomized study of long-term anticoagulation therapy for Asian and non-Asian patients with atrial fibrillation by using 2 doses of dabigatran etexilate (DE) versus warfarin on several types of stroke and bleeding rates. They handled 2782 Asian patients and 15 331 non-Asian patients, and Cox regression model was applied for risk assessment.1Hemorrhagic stroke was significantly reduced by using DE 110 mg and DE 150 mg versus warfarin in Asian patients, presenting hazard ratios (95% confidence interval) of 0.15 (0.03–0.66) and 0.22 (0.06–0.77), respectively. In non-Asian patients, hazard ratios (95% confidence interval) of DE 110 mg and DE 150 mg versus warfarin …

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