Open AccessAntiplatelet Loading Improves Behavioral Outcome in a Rabbit Model of Stroke
Author(s) -
Dawn Meyer,
Peggy Compton,
JoAnn Eastwood,
Karen H. Gylys,
Justin A. Zivin
Publication year - 2013
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.113.002565
Subject(s) - medicine , aspirin , clopidogrel , stroke (engine) , platelet , anesthesia , arachidonic acid , loading dose , antiplatelet drug , cardiology , pharmacology , mechanical engineering , biochemistry , chemistry , engineering , enzyme
No approved acute therapy exists for thousands of patients with ischemic stroke who present ineligible for thrombolytics. The purpose of this proof-of-concept study was to evaluate the efficacy of acute antiplatelet loading on stroke outcome in the rabbit small clot embolic model.
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