MMP9 Variation After Thrombolysis Is Associated With Hemorrhagic Transformation of Lesion and Death | Zendy

Domenico Inzitari | Zendy; Betti Giusti | Zendy; Patrizia Nencini | Zendy; Anna Maria Gori | Zendy; Mascia Nesi | Zendy; Vanessa Palumbo | Zendy; Benedetta Piccardi | Zendy; Alessandra Armillis | Zendy; Giovanni Pracucci | Zendy; Giorgio Bono | Zendy; Paolo Bovi | Zendy; Domenico Consoli | Zendy; Mario Guidotti | Zendy; Antonia Nucera | Zendy; Francesca Massaro | Zendy; Giuseppe Micieli | Zendy; Giovanni Orlandi | Zendy; Francesco Perini | Zendy; Rossana Tassi | Zendy; Maria Rosaria Tola | Zendy; Maria Sessa | Zendy; Danilo Toni | Zendy; Rosanna Abbate | Zendy

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MMP9 Variation After Thrombolysis Is Associated With Hemorrhagic Transformation of Lesion and Death

Author(s) -

Domenico Inzitari,

Betti Giusti,

Patrizia Nencini,

Anna Maria Gori,

Mascia Nesi,

Vanessa Palumbo,

Benedetta Piccardi,

Alessandra Armillis,

Giovanni Pracucci,

Giorgio Bono,

Paolo Bovi,

Domenico Consoli,

Mario Guidotti,

Antonia Nucera,

Francesca Massaro,

Giuseppe Micieli,

Giovanni Orlandi,

Francesco Perini,

Rossana Tassi,

Maria Rosaria Tola,

Maria Sessa,

Danilo Toni,

Rosanna Abbate

Publication year - 2013

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.113.002274

Subject(s) - medicine , modified rankin scale , intracerebral hemorrhage , thrombolysis , odds ratio , stroke (engine) , confidence interval , tissue plasminogen activator , lesion , matrix metalloproteinase , gastroenterology , surgery , ischemia , ischemic stroke , myocardial infarction , subarachnoid hemorrhage , mechanical engineering , engineering

Experimentally, matrix metalloproteinases (MMPs) play a detrimental role related to hemorrhagic transformation and severity of an ischemic brain lesion. Tissue-type plasminogen activator (tPA) enhances such effects. This study aimed to expand clinical evidence in this connection.

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