Improving the Efficiency of Stroke Trials | Zendy

Kate McArthur | Zendy; P. Johnson | Zendy; Terence J. Quinn | Zendy; Peter Higgins | Zendy; Peter Langhorne | Zendy; Matthew R. Walters | Zendy; Christopher J. Weir | Zendy; Jesse Dawson | Zendy; Kennedy R. Lees | Zendy

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Improving the Efficiency of Stroke Trials

Author(s) -

Kate McArthur,

P. Johnson,

Terence J. Quinn,

Peter Higgins,

Peter Langhorne,

Matthew R. Walters,

Christopher J. Weir,

Jesse Dawson,

Kennedy R. Lees

Publication year - 2013

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.113.002266

Subject(s) - medicine , intraclass correlation , confidence interval , sample size determination , adjudication , stroke (engine) , modified rankin scale , reliability (semiconductor) , inter rater reliability , physical therapy , statistics , rating scale , psychometrics , ischemic stroke , mathematics , law , engineering , mechanical engineering , clinical psychology , power (physics) , physics , ischemia , quantum mechanics , political science

Use of the modified Rankin scale (mRS) in multicenter trials may be limited by interobserver variability. We assessed the effect of this on trial power and developed a novel group adjudication approach.

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