Regulatory T Cells in Ischemic Stroke
Author(s) -
WolfRüdiger Schäbitz
Publication year - 2013
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.113.002228
Subject(s) - medicine , stroke (engine) , ischemic stroke , cardiology , ischemia , mechanical engineering , engineering
Research in the cerebrovascular field has focused recently on stroke-associated inflammatory processes. These studies produced important results and demonstrated, for instance, that stroke-associated infections are a substantial risk factor for a stroke to occur.1 In addition, the stroke itself was associated with an immunodeficiency-like syndrome.2 This immunodeficient constellation is currently thought to act as a potential inducer for poststroke infections, such as pneumonia, and to influence the final neurological outcome. Consequently, early clinical trials tested the hypothesis of improving outcome preventing infections by a prophylactic antibiotic treatment. These studies indeed revealed reduced …
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