Preclinical Stroke Research | Zendy

David A. Greenberg | Zendy

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Preclinical Stroke Research

Author(s) -

David A. Greenberg

Publication year - 2013

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.113.002088

Subject(s) - medicine , stroke (engine) , disappointment , extant taxon , disease , stroke recovery , intensive care medicine , neuroscience , physical therapy , pathology , psychotherapist , psychology , mechanical engineering , engineering , evolutionary biology , rehabilitation , biology

The Stroke Progress Review Group, commissioned by National Institute of Neurological Disorders and Stroke to review the status of stroke research in 2011, addressed a variety of clinical and preclinical areas, including progress and unmet needs in preclinical investigation.1 Identified among the latter were the need to develop better molecular, cellular, and animal models of stroke. This finding reflects understandable disappointment that, although such models have been available for >50 years,2 few advances in the treatment of acute stroke have occurred. Numerous authors have addressed possible explanations for this paradox and recommended new approaches,3–6 and the Stroke Progress Review Group produced no new conceptual breakthroughs in this respect. However, there may be value in reflecting again on some of the …

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