Cortical Photothrombotic Infarcts Impair the Recall of Previously Acquired Memories but Spare the Formation of New Ones | Zendy

Kai Diederich | Zendy; Antje Schmidt | Zendy; JanKolja Strecker | Zendy; WolfRüdiger Schäbitz | Zendy; Matthias Schilling | Zendy; Jens Minnerup | Zendy

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Cortical Photothrombotic Infarcts Impair the Recall of Previously Acquired Memories but Spare the Formation of New Ones

Author(s) -

Kai Diederich,

Antje Schmidt,

JanKolja Strecker,

WolfRüdiger Schäbitz,

Matthias Schilling,

Jens Minnerup

Publication year - 2013

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.113.001907

Subject(s) - medicine , stroke (engine) , morris water navigation task , dementia , cognition , neuroscience , recall , physical medicine and rehabilitation , hippocampal formation , psychology , psychiatry , mechanical engineering , disease , engineering , cognitive psychology

Despite a high incidence of poststroke dementia, there is no specific treatment for this condition. Because the evaluation of poststroke cognitive deficits in animal models of stroke is exceedingly challenging, the preclinical evaluation of candidate drugs is limited. We aimed to explore the impact of small cortical photothrombotic strokes on poststroke cognition, thereby assessing the suitability of this experimental stroke model for the investigation of cognitive impairment after stroke.

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