Ischemic Stroke Brain Sends Indirect Cell Death Signals to the Heart | Zendy

Hiroto Ishikawa | Zendy; Naoki Tajiri | Zendy; Julie Vasconcellos | Zendy; Yuji Kaneko | Zendy; Osamu Mimura | Zendy; Mari Dezawa | Zendy; Cesar V. Borlongan | Zendy

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Ischemic Stroke Brain Sends Indirect Cell Death Signals to the Heart

Author(s) -

Hiroto Ishikawa,

Naoki Tajiri,

Julie Vasconcellos,

Yuji Kaneko,

Osamu Mimura,

Mari Dezawa,

Cesar V. Borlongan

Publication year - 2013

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.113.001714

Subject(s) - medicine , myocyte , stroke (engine) , programmed cell death , ischemia , cardiac myocyte , cardiology , apoptosis , necrosis , pathological , pathology , biology , mechanical engineering , engineering , biochemistry

Ischemic stroke is a leading cause of mortality and morbidity in the world and may be associated with cardiac myocyte vulnerability. However, it remains uncertain how an ischemic brain contributes to cardiac alternations. Here, we used experimental stroke models to reveal the pathological effects of the ischemic brain on the heart.

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