Serum Brain–Derived Neurotrophic Factor and Vascular Endothelial Growth Factor Levels Are Associated With Risk of Stroke and Vascular Brain Injury | Zendy

Aleksandra Pikula | Zendy; Alexa S. Beiser | Zendy; Tai C. Chen | Zendy; Sarah R. Preis | Zendy; Demetrios Vorgias | Zendy; Charles DeCarli | Zendy; Rhoda Au | Zendy; Margaret KellyHayes | Zendy; Carlos S. Kase | Zendy; Philip A. Wolf | Zendy; Ramachandran S. Vasan | Zendy; Sudha Seshadri | Zendy

Open Access

Serum Brain–Derived Neurotrophic Factor and Vascular Endothelial Growth Factor Levels Are Associated With Risk of Stroke and Vascular Brain Injury

Author(s) -

Aleksandra Pikula,

Alexa S. Beiser,

Tai C. Chen,

Sarah R. Preis,

Demetrios Vorgias,

Charles DeCarli,

Rhoda Au,

Margaret KellyHayes,

Carlos S. Kase,

Philip A. Wolf,

Ramachandran S. Vasan,

Sudha Seshadri

Publication year - 2013

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.113.001447

Subject(s) - medicine , stroke (engine) , vascular endothelial growth factor , risk factor , brain derived neurotrophic factor , neurotrophic factors , vascular disease , cardiology , vegf receptors , receptor , mechanical engineering , engineering

Brain-derived neurotrophic factor (BDNF), a major neurotrophin and vascular endothelial growth factor (VEGF) have a documented role in neurogenesis, angiogenesis, and neuronal survival. In animal experiments, they impact infarct size and functional motor recovery after an ischemic brain lesion. We sought to examine the association of serum BDNF and VEGF with the risk of clinical stroke or subclinical vascular brain injury in a community-based sample.

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