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The Effect of Lacunar Infarcts on White Matter Tract Integrity
Author(s) -
Yaël D. Reijmer,
Whitney M. Freeze,
Alexander Leemans,
Geert Jan Biessels
Publication year - 2013
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.113.001321
Subject(s) - diffusion mri , medicine , white matter , pyramidal tracts , fractional anisotropy , lesion , corticospinal tract , tractography , optic tract , hyperintensity , pathology , cardiology , magnetic resonance imaging , radiology , anatomy , optic nerve
Lacunar infarcts may cause disturbances of the white matter (WM) structure remote from the primary lesion. Here, we used diffusion MRI and tractography to (1) spatially characterize microstructural abnormalities along WM tracts containing a lacunar infarct and (2) relate abnormalities in remote parts of the affected WM tract to cognitive outcome.

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