Apolipoprotein E, Statins, and Risk of Intracerebral Hemorrhage | Zendy

Daniel Woo | Zendy; Ranjan Deka | Zendy; Guido J. Falcone | Zendy; Matthew L. Flaherty | Zendy; Mary Haverbusch | Zendy; Sharyl Martini | Zendy; Steven M. Greenberg | Zendy; Alison Ayres | Zendy; Laura Sauerbeck | Zendy; Brett Kissela | Zendy; Dawn Kleindorfer | Zendy; Charles J. Moomaw | Zendy; Christopher D. Anderson | Zendy; Joseph P. Broderick | Zendy; Jonathan Rosand | Zendy; Carl D. Langefeld | Zendy; Jessica G. Woo | Zendy

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Apolipoprotein E, Statins, and Risk of Intracerebral Hemorrhage

Author(s) -

Daniel Woo,

Ranjan Deka,

Guido J. Falcone,

Matthew L. Flaherty,

Mary Haverbusch,

Sharyl Martini,

Steven M. Greenberg,

Alison Ayres,

Laura Sauerbeck,

Brett Kissela,

Dawn Kleindorfer,

Charles J. Moomaw,

Christopher D. Anderson,

Joseph P. Broderick,

Jonathan Rosand,

Carl D. Langefeld,

Jessica G. Woo

Publication year - 2013

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.113.001304

Subject(s) - medicine , intracerebral hemorrhage , statin , stroke (engine) , exact test , cohort study , cohort , prospective cohort study , apolipoprotein e , disease , subarachnoid hemorrhage , mechanical engineering , engineering

Apolipoprotein E (ApoE) genotypes have been associated with lobar intracerebral hemorrhage (ICH). Although statins have been associated with an increased risk of ICH, meta-analyses have not consistently shown a statin-induced risk of ICH. Here, we test whether hypercholesterolemia (HC) and ApoE polymorphisms affect the risk of ICH by statin use.

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