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Stroke Patients Develop Antibodies That React With Components of N -Methyl- d -Aspartate Receptor Subunit 1 in Proportion to Lesion Size
Author(s) -
Maggie L. KalevZylinska,
W. Langford Symes,
Kevin C.E. Little,
Peng Sun,
Daying Wen,
Linzi Qiao,
Deborah Young,
Matthew J. During,
P. Alan Barber
Publication year - 2013
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.113.001235
Subject(s) - medicine , antibody , stroke (engine) , western blot , immunohistochemistry , blot , receptor , recombinant dna , pathology , lesion , immunology , biology , biochemistry , mechanical engineering , engineering , gene
Antibodies against neuronal antigens develop in patients after stroke and some may serve as biomarkers of neuronal injury. We aimed to determine whether antibodies against subunit 1 (GluN1) of the N-methyl-D-aspartate receptor also develop after stroke and if so, whether they correlate with stroke characteristics.

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