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In recent contribution of Stroke , Ni Chroinin et al1 reported that in patients treated with intravenous thrombolysis, statin treatment at stroke onset was not associated with favorable functional outcome (modified Rankin Scale, ≤2) at 90 days (odds ratio [OR], 1.01; 95% confidence interval [CI], 0.88–1.15; P =0.93, data available from 5 observational studies, 4993 patients). Also, it was associated with an increased fatality at 90 days (pooled OR, 1.25; 95% CI, 1.02–1.52; P =0.03, 3 observational studies, 4339 patients), although this association was not observed after adjustment for potential confounding variables.The main point concerns the eligibility to intravenous thrombolysis for patients under statin treatment at stroke onset. The following 2 observations are given to illustrate …

stroke

Letter by Cappellari et al Regarding Article, “Statin Therapy and Outcome After Ischemic Stroke: Systematic Review and Meta-analysis of Observational Studies and Randomized Trials”