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Cerebral Ischemia and Reperfusion Increases the Heterogeneity of Local Oxygen Supply/Consumption Balance
Author(s) -
Harvey R. Weiss,
Jeremy Grayson,
Xia Liu,
Sylviana Barsoum,
Harsh Shah,
Oak Z.
Publication year - 2013
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.113.001172
Subject(s) - medicine , ischemia , consumption (sociology) , balance (ability) , cardiology , stroke (engine) , oxygen , anesthesia , physical medicine and rehabilitation , mechanical engineering , social science , chemistry , organic chemistry , sociology , engineering
After cerebral vessel blockage, local blood flow and O2 consumption becomes lower and oxygen extraction increases. With reperfusion, blood flow is partially restored. We examined the effects of ischemia-reperfusion on the heterogeneity of local venous oxygen saturation in rats in order to determine the pattern of microregional O2 supply/consumption balance in reperfusion.

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