Gamma Aminobutyric Acid Receptor Agonists for Acute Stroke | Zendy

Jia Liu | Zendy; Luning Wang | Zendy

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Gamma Aminobutyric Acid Receptor Agonists for Acute Stroke

Author(s) -

Jia Liu,

Luning Wang

Publication year - 2013

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.113.001121

Subject(s) - medicine , stroke (engine) , modified rankin scale , neurology , adverse effect , placebo , ischemic stroke , psychiatry , ischemia , alternative medicine , mechanical engineering , pathology , engineering

Gamma aminobutyric acid (GABA) receptor agonists have shown to be effective in reducing infarct size and improving functional outcome in animal models of cerebral ischemia. However, the sedation effects of GABA receptor agonists limited the application in acute stroke patients because of the potential risk of stupor. ObjectiveThe aim of this study is to determine the efficacy and safety of GABA receptor agonists in the treatment of acute stroke. Types of StudiesRandomized controlled trials. Types of ParticipantsAcute stroke patients within 12 hours after stroke onset. Types of InterventionsGABA receptor agonists in …

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