CYP2C19 Polymorphisms and Antiplatelet Effects of Clopidogrel in Acute Ischemic Stroke in China | Zendy

Dongmei Jia | Zendy; Zhibin Chen | Zendy; Meijuan Zhang | Zendy; Wenjie Yang | Zendy; Jiali Jin | Zendy; Yongquan Xia | Zendy; Chunlei Zhang | Zendy; Yuan Shao | Zendy; Cong Chen | Zendy; Yun Xu | Zendy

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CYP2C19 Polymorphisms and Antiplatelet Effects of Clopidogrel in Acute Ischemic Stroke in China

Author(s) -

Dongmei Jia,

Zhibin Chen,

Meijuan Zhang,

Wenjie Yang,

Jiali Jin,

Yongquan Xia,

Chunlei Zhang,

Yuan Shao,

Cong Chen,

Yun Xu

Publication year - 2013

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.113.000823

Subject(s) - clopidogrel , medicine , cyp2c19 , p2y12 , stroke (engine) , modified rankin scale , aspirin , cardiology , ischemic stroke , ischemia , mechanical engineering , cytochrome p450 , metabolism , engineering

Little research regarding genotypes and clopidogrel response related to acute ischemic stroke has been published. This study was conducted to investigate whether the polymorphisms of receptors or enzymes involved in the metabolic process of clopidogrel affect clopidogrel response and prognosis related to acute stroke.

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