Intra-arterial Cell Transplantation Provides Timing-Dependent Cell Distribution and Functional Recovery After Stroke | Zendy

Shunsuke Ishizaka | Zendy; Nobutaka Horie | Zendy; Katsuya Satoh | Zendy; Yuhtaka Fukuda | Zendy; Noriyuki Nishida | Zendy; Izumi Nagata | Zendy

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Intra-arterial Cell Transplantation Provides Timing-Dependent Cell Distribution and Functional Recovery After Stroke

Author(s) -

Shunsuke Ishizaka,

Nobutaka Horie,

Katsuya Satoh,

Yuhtaka Fukuda,

Noriyuki Nishida,

Izumi Nagata

Publication year - 2013

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.112.677328

Subject(s) - medicine , transplantation , angiogenesis , neurotrophic factors , microglia , mesenchymal stem cell , neuroprotection , stroke (engine) , stroke recovery , astrocyte , cell therapy , stem cell therapy , cerebral infarction , neuroscience , ischemia , stem cell , pathology , central nervous system , inflammation , microbiology and biotechnology , biology , rehabilitation , receptor , mechanical engineering , engineering , physical therapy

Intra-arterial cell transplantation offers a novel therapeutic strategy for stroke; however, it remains unclear how the timing of cell administration affects cell distribution, brain repair processes, and functional recovery. Here, we investigate the hypothesis that the timing of cell transplantation changes the behavior of the cell graft and the host environment in a way that affects functional recovery.

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