Burden of Blood Pressure–Related Alleles Is Associated With Larger Hematoma Volume and Worse Outcome in Intracerebral Hemorrhage
Author(s) -
Guido J. Falcone,
Alessandro Biffi,
William J. Devan,
H. Bart Brouwers,
Christopher D. Anderson,
Valerie Valant,
Alison Ayres,
Kristin Schwab,
Natalia S. Rost,
Joshua N. Goldstein,
Anand Viswanathan,
Steven M. Greenberg,
Magdy Selim,
James F. Meschia,
Devin L. Brown,
Bradford B. Worrall,
Scott Silliman,
David Tirschwell,
Jonathan Rosand
Publication year - 2013
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.112.675181
Subject(s) - medicine , intracerebral hemorrhage , hematoma , stroke (engine) , blood pressure , cardiology , anesthesia , surgery , subarachnoid hemorrhage , mechanical engineering , engineering
Intracerebral hemorrhage (ICH) is the acute manifestation of a progressive disease of the cerebral small vessels. The severity of this disease seems to influence not only risk of ICH but also the size of the hematoma. As the burden of high blood pressure-related alleles is associated with both hypertension-related end-organ damage and risk of ICH, we sought to determine whether this burden influences ICH baseline hematoma volume.
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