Association of Molecular Markers With Perihematomal Edema and Clinical Outcome in Intracerebral Hemorrhage | Zendy

Na Li | Zendy; Yan Fang Liu | Zendy; Li Ma | Zendy; Hans Worthmann | Zendy; Yi Wang | Zendy; Yong Jun Wang | Zendy; Yi Pei Gao | Zendy; Peter Raab | Zendy; Reinhard Dengler | Zendy; Karin Weißenborn | Zendy; Xing Zhao | Zendy

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Association of Molecular Markers With Perihematomal Edema and Clinical Outcome in Intracerebral Hemorrhage

Author(s) -

Na Li,

Yan Fang Liu,

Li Ma,

Hans Worthmann,

Yi Wang,

Yong Jun Wang,

Yi Pei Gao,

Peter Raab,

Reinhard Dengler,

Karin Weißenborn,

Xing Zhao

Publication year - 2013

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.112.673590

Subject(s) - medicine , intracerebral hemorrhage , modified rankin scale , hematoma , edema , odds ratio , anesthesia , stroke (engine) , gastroenterology , cerebral edema , vascular endothelial growth factor , pathology , surgery , subarachnoid hemorrhage , ischemic stroke , ischemia , mechanical engineering , engineering , vegf receptors

Perihematomal edema contributes to secondary brain injury in intracerebral hemorrhage (ICH). Increase of matrix metalloproteinases (MMPs) and growth factors is considerably involved in blood-brain barrier disruption and neuronal cell death in ICH models. We therefore hypothesized that increased levels of these molecular markers are associated with perihematomal edema and clinical outcome in ICH patients.

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