Common Variants Within Oxidative Phosphorylation Genes Influence Risk of Ischemic Stroke and Intracerebral Hemorrhage | Zendy

Christopher D. Anderson | Zendy; Alessandro Biffi | Zendy; Michael A. Nalls | Zendy; William J. Devan | Zendy; Kristin Schwab | Zendy; Alison Ayres | Zendy; Valerie Valant | Zendy; Owen A. Ross | Zendy; Natalia S. Rost | Zendy; Richa Saxena | Zendy; Anand Viswanathan | Zendy; Bradford B. Worrall | Zendy; Thomas G. Brott | Zendy; Joshua N. Goldstein | Zendy; Devin L. Brown | Zendy; Joseph P. Broderick | Zendy; Bo Norrving | Zendy; Steven M. Greenberg | Zendy; Scott Silliman | Zendy; Björn M. Hansen | Zendy; David Tirschwell | Zendy; Arne Lindgren | Zendy; Agnieszka Słowik | Zendy; Reinhold Schmidt | Zendy; Magdy Selim | Zendy; Jaume Roquer | Zendy; Joan Montaner | Zendy; Andrew Singleton | Zendy; Chelsea S. Kidwell | Zendy; Daniel Woo | Zendy; Karen L. Furie | Zendy; James F. Meschia | Zendy; Jonathan Rosand | Zendy

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Common Variants Within Oxidative Phosphorylation Genes Influence Risk of Ischemic Stroke and Intracerebral Hemorrhage

Author(s) -

Christopher D. Anderson,

Alessandro Biffi,

Michael A. Nalls,

William J. Devan,

Kristin Schwab,

Alison Ayres,

Valerie Valant,

Owen A. Ross,

Natalia S. Rost,

Richa Saxena,

Anand Viswanathan,

Bradford B. Worrall,

Thomas G. Brott,

Joshua N. Goldstein,

Devin L. Brown,

Joseph P. Broderick,

Bo Norrving,

Steven M. Greenberg,

Scott Silliman,

Björn M. Hansen,

David Tirschwell,

Arne Lindgren,

Agnieszka Słowik,

Reinhold Schmidt,

Magdy Selim,

Jaume Roquer,

Joan Montaner,

Andrew Singleton,

Chelsea S. Kidwell,

Daniel Woo,

Karen L. Furie,

James F. Meschia,

Jonathan Rosand

Publication year - 2013

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.112.672089

Subject(s) - medicine , intracerebral hemorrhage , stroke (engine) , cohort , odds ratio , gene , oxidative phosphorylation , bioinformatics , mitochondrial dna , genetic association , genome wide association study , candidate gene , genetics , single nucleotide polymorphism , genotype , biology , biochemistry , subarachnoid hemorrhage , mechanical engineering , engineering

Previous studies demonstrated association between mitochondrial DNA variants and ischemic stroke (IS). We investigated whether variants within a larger set of oxidative phosphorylation (OXPHOS) genes encoded by both autosomal and mitochondrial DNA were associated with risk of IS and, based on our results, extended our investigation to intracerebral hemorrhage (ICH).

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