Multiparametric MRI and CT Models of Infarct Core and Favorable Penumbral Imaging Patterns in Acute Ischemic Stroke
Author(s) -
Chelsea S. Kidwell,
Max Wintermark,
Deidre Anne De Silva,
Timothy J. Schaewe,
Reza Jahan,
Sidney Starkman,
Tudor Jovin,
Jason Hom,
Mouhammad Jumaa,
Jeffrie Schreier,
Jeffrey Gornbein,
David S. Liebeskind,
Jeffry R. Alger,
Jeffrey L. Saver
Publication year - 2012
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.112.670034
Subject(s) - penumbra , medicine , voxel , magnetic resonance imaging , stroke (engine) , radiology , core (optical fiber) , acute stroke , neuroimaging , infarction , nuclear medicine , ischemia , cardiology , myocardial infarction , mechanical engineering , materials science , psychiatry , tissue plasminogen activator , engineering , composite material
Objective imaging methods to identify optimal candidates for late recanalization therapies are needed. The study goals were (1) to develop magnetic resonance imaging (MRI) and computed tomography (CT) multiparametric, voxel-based predictive models of infarct core and penumbra in acute ischemic stroke patients, and (2) to develop patient-level imaging criteria for favorable penumbral pattern based on good clinical outcome in response to successful recanalization.
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