Impairment of Cerebral Autoregulation Predicts Delayed Cerebral Ischemia After Subarachnoid Hemorrhage | Zendy

Karol P. Budohoski | Zendy; Marek Czosnyka | Zendy; Peter Smielewski | Zendy; Magdalena Kasprowicz | Zendy; Adel Helmy | Zendy; Diederik Bulters | Zendy; John D. Pickard | Zendy; Peter J. Kirkpatrick | Zendy

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Impairment of Cerebral Autoregulation Predicts Delayed Cerebral Ischemia After Subarachnoid Hemorrhage

Author(s) -

Karol P. Budohoski,

Marek Czosnyka,

Peter Smielewski,

Magdalena Kasprowicz,

Adel Helmy,

Diederik Bulters,

John D. Pickard,

Peter J. Kirkpatrick

Publication year - 2012

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.112.669788

Subject(s) - medicine , vasospasm , transcranial doppler , subarachnoid hemorrhage , odds ratio , cerebral vasospasm , anesthesia , confidence interval , autoregulation , ischemia , cardiology , blood pressure

Delayed cerebral ischemia (DCI) is a recognized contributor to unfavorable outcome after subarachnoid hemorrhage (SAH). Recent data challenge the concept of vasospasm as the sole cause of ischemia and suggest a multifactorial process with dysfunctional cerebral autoregulation as a component. We tested the hypothesis that early autoregulatory failure, detected using near-infrared spectroscopy-based index, TOxa and transcranial Doppler-based index, Sxa, can predict DCI.

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