Remodeling of the Axon Initial Segment After Focal Cortical and White Matter Stroke | Zendy

Jason D. Hinman | Zendy; Matthew N. Rasband | Zendy; S. Thomas Carmichael | Zendy

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Remodeling of the Axon Initial Segment After Focal Cortical and White Matter Stroke

Author(s) -

Jason D. Hinman,

Matthew N. Rasband,

S. Thomas Carmichael

Publication year - 2012

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.112.668749

Subject(s) - biotinylated dextran amine , white matter , medicine , stroke (engine) , neuroplasticity , cortex (anatomy) , axon , forelimb , neuroscience , cerebral cortex , stroke recovery , anatomy , biology , magnetic resonance imaging , radiology , mechanical engineering , rehabilitation , engineering

Recovery from stroke requires neuroplasticity within surviving adjacent cortex. The axon initial segment (AIS) is the site of action potential initiation and a focal point for tuning of neuronal excitability. Remodeling of the AIS may be important to neuroplasticity after stroke.

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