B Vitamins and Magnetic Resonance Imaging–Detected Ischemic Brain Lesions in Patients With Recent Transient Ischemic Attack or Stroke | Zendy

Margherita Cavalieri | Zendy; Reinhold Schmidt | Zendy; Christopher Chen | Zendy; Vincent Mok | Zendy; Gabriel R. de Freitas | Zendy; Swithin Song | Zendy; Qilong Yi | Zendy; Stefan Ropele | Zendy; Anja Grazer | Zendy; Nina Homayoon | Zendy; Christian Enzinger | Zendy; K. Loh | Zendy; Ka Sing Wong | Zendy; Adrian Wong | Zendy; Yunyun Xiong | Zendy; Hui Meng Chang | Zendy; Meng Cheong Wong | Zendy; Franz Fazekas | Zendy; John W. Eikelboom | Zendy; Graeme J. Hankey | Zendy

Open Access

B Vitamins and Magnetic Resonance Imaging–Detected Ischemic Brain Lesions in Patients With Recent Transient Ischemic Attack or Stroke

Author(s) -

Margherita Cavalieri,

Reinhold Schmidt,

Christopher Chen,

Vincent Mok,

Gabriel R. de Freitas,

Swithin Song,

Qilong Yi,

Stefan Ropele,

Anja Grazer,

Nina Homayoon,

Christian Enzinger,

K. Loh,

Ka Sing Wong,

Adrian Wong,

Yunyun Xiong,

Hui Meng Chang,

Meng Cheong Wong,

Franz Fazekas,

John W. Eikelboom,

Graeme J. Hankey

Publication year - 2012

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.112.665703

Subject(s) - medicine , hyperintensity , stroke (engine) , placebo , b vitamins , white matter , homocysteine , magnetic resonance imaging , gastroenterology , cardiology , pathology , radiology , mechanical engineering , alternative medicine , engineering

Elevated concentrations of homocysteine are associated with cerebral small vessel disease (CSVD). B-vitamin supplementation with folate and vitamins B12 and B6 reduces homocysteine concentrations. In a substudy of the VITAmins TO Prevent Stroke (VITATOPS) trial, we assessed the hypothesis that the addition of once-daily supplements of B vitamins would reduce the progression of CSVD-related brain lesions.

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