Extensive White Matter Hyperintensities May Increase Brain Volume in Cerebral Autosomal-Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy
Author(s) -
Ming Yao,
Éric Jouvent,
Marco Düring,
O Godin,
Dominique Hervé,
J.-P. Guichard,
YiCheng Zhu,
Andreas Gschwendtner,
Christian Opherk,
Martin Dichgans,
Hugues Chabriat
Publication year - 2012
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.112.664854
Subject(s) - medicine , leukoencephalopathy , cadasil , hyperintensity , white matter , stroke (engine) , pathology , magnetic resonance imaging , cardiology , radiology , disease , mechanical engineering , engineering
The extent of white matter hyperintensities (WMH) is associated with cerebral atrophy in elderly people. WMH is a radiological hallmark of cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), but their relationship with brain volume remains poorly understood. The association between WMH and brain volume was analyzed in a large population of patients with CADASIL.
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