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Aberrant Neurogenesis After Stroke
Author(s) -
Fanny Niv,
Silke Keiner,
Krishna Kumar,
Otto W. Witte,
D. Chichung Lie,
Christoph Redecker
Publication year - 2012
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.112.660977
Subject(s) - neurogenesis , dentate gyrus , hippocampal formation , neuroscience , medicine , neuroplasticity , granule cell , stroke (engine) , dendritic spine , pathology , anatomy , biology , mechanical engineering , engineering
Adult neurogenesis in the dentate gyrus is a unique form of brain plasticity that is strongly stimulated after stroke. We investigate the morphological properties of new granule cells, which are born and develop after the ischemic insult, and query whether these adult-born neurons properly integrate into the pre-existing hippocampal circuitries.

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