Burden of Risk Alleles for Hypertension Increases Risk of Intracerebral Hemorrhage | Zendy

Guido J. Falcone | Zendy; Alessandro Biffi | Zendy; William J. Devan | Zendy; Jeremiasz Jagiełła | Zendy; Helena Schmidt | Zendy; Brett Kissela | Zendy; Björn M. Hansen | Zendy; Jordi JiménezConde | Zendy; Eva GiraltSteinhauer | Zendy; Roberto Elosúa | Zendy; Elisa CuadradoGodia | Zendy; Carolina SorianoTárraga | Zendy; Alison Ayres | Zendy; Kristin Schwab | Zendy; Joanna Pera | Zendy; Andrzej Urbanik | Zendy; Natalia S. Rost | Zendy; Joshua N. Goldstein | Zendy; Anand Viswanathan | Zendy; Alexander Pichler | Zendy; Christian Enzinger | Zendy; Bo Norrving | Zendy; David Tirschwell | Zendy; Magdy Selim | Zendy; Devin L. Brown | Zendy; Scott Silliman | Zendy; Bradford B. Worrall | Zendy; James F. Meschia | Zendy; Chelsea S. Kidwell | Zendy; Joan Montaner | Zendy; Israel FernándezCadenas | Zendy; Pilar Delgado | Zendy; Joseph P. Broderick | Zendy; Steven M. Greenberg | Zendy; Jaume Roquer | Zendy; Arne Lindgren | Zendy; Agnieszka Słowik | Zendy; Reinhold Schmidt | Zendy; Matthew L. Flaherty | Zendy; Dawn Kleindorfer | Zendy; Carl D. Langefeld | Zendy; Daniel Woo | Zendy; Jonathan Rosand | Zendy

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Burden of Risk Alleles for Hypertension Increases Risk of Intracerebral Hemorrhage

Author(s) -

Guido J. Falcone,

Alessandro Biffi,

William J. Devan,

Jeremiasz Jagiełła,

Helena Schmidt,

Brett Kissela,

Björn M. Hansen,

Jordi JiménezConde,

Eva GiraltSteinhauer,

Roberto Elosúa,

Elisa CuadradoGodia,

Carolina SorianoTárraga,

Alison Ayres,

Kristin Schwab,

Joanna Pera,

Andrzej Urbanik,

Natalia S. Rost,

Joshua N. Goldstein,

Anand Viswanathan,

Alexander Pichler,

Christian Enzinger,

Bo Norrving,

David Tirschwell,

Magdy Selim,

Devin L. Brown,

Scott Silliman,

Bradford B. Worrall,

James F. Meschia,

Chelsea S. Kidwell,

Joan Montaner,

Israel FernándezCadenas,

Pilar Delgado,

Joseph P. Broderick,

Steven M. Greenberg,

Jaume Roquer,

Arne Lindgren,

Agnieszka Słowik,

Reinhold Schmidt,

Matthew L. Flaherty,

Dawn Kleindorfer,

Carl D. Langefeld,

Daniel Woo,

Jonathan Rosand

Publication year - 2012

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.112.659755

Subject(s) - medicine , intracerebral hemorrhage , single nucleotide polymorphism , blood pressure , logistic regression , snp , case control study , risk factor , prospective cohort study , family history , genotype , genetics , subarachnoid hemorrhage , gene , biology

Genetic variation influences risk of intracerebral hemorrhage (ICH). Hypertension (HTN) is a potent risk factor for ICH and several common genetic variants (single nucleotide polymorphisms [SNPs]) associated with blood pressure levels have been identified. We sought to determine whether the cumulative burden of blood pressure-related SNPs is associated with risk of ICH and pre-ICH diagnosis of HTN.

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