Stroke Assessment With Diffusional Kurtosis Imaging | Zendy

Edward S. Hui | Zendy; Els Fieremans | Zendy; Jens H. Jensen | Zendy; Ali Tabesh | Zendy; Wuwei Feng | Zendy; Leonardo Bonilha | Zendy; Maria Vittoria Spampinato | Zendy; Robert J. Adams | Zendy; Joseph A. Helpern | Zendy

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Stroke Assessment With Diffusional Kurtosis Imaging

Author(s) -

Edward S. Hui,

Els Fieremans,

Jens H. Jensen,

Ali Tabesh,

Wuwei Feng,

Leonardo Bonilha,

Maria Vittoria Spampinato,

Robert J. Adams,

Joseph A. Helpern

Publication year - 2012

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.112.657742

Subject(s) - kurtosis , medicine , diffusion mri , effective diffusion coefficient , ischemia , white matter , lesion , stroke (engine) , diffusion , ischemic stroke , magnetic resonance imaging , radiology , nuclear medicine , pathology , cardiology , mechanical engineering , statistics , physics , mathematics , engineering , thermodynamics

Despite being the gold standard technique for stroke assessment, conventional diffusion MRI provides only partial information about tissue microstructure. Diffusional kurtosis imaging is an advanced diffusion MRI method that yields, in addition to conventional diffusion information, the diffusional kurtosis, which may help improve characterization of tissue microstructure. In particular, this additional information permits the description of white matter (WM) in terms of WM-specific diffusion metrics. The goal of this study is to elucidate possible biophysical mechanisms underlying ischemia using these new WM metrics.

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