Cerebral White Matter Lesions and Lacunar Infarcts Contribute to the Presence of Mild Parkinsonian Signs | Zendy

Karlijn F. de Laat | Zendy; Anouk G.W. van Norden | Zendy; Rob A.R. Gons | Zendy; Inge W.M. van Uden | Zendy; Marcel P. Zwiers | Zendy; Bastiaan R. Bloem | Zendy; Ewoud J. van Dijk | Zendy; Frank–Erik de Leeuw | Zendy

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Cerebral White Matter Lesions and Lacunar Infarcts Contribute to the Presence of Mild Parkinsonian Signs

Author(s) -

Karlijn F. de Laat,

Anouk G.W. van Norden,

Rob A.R. Gons,

Inge W.M. van Uden,

Marcel P. Zwiers,

Bastiaan R. Bloem,

Ewoud J. van Dijk,

Frank–Erik de Leeuw

Publication year - 2012

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.112.657130

Subject(s) - medicine , lacunar stroke , white matter , hyperintensity , perivascular space , parkinsonism , disease , pathology , stroke (engine) , lesion , magnetic resonance imaging , leukoaraiosis , dementia , cardiology , radiology , ischemia , ischemic stroke , mechanical engineering , engineering

Mild parkinsonian signs (MPS) are common in elderly people and may be an early stage of parkinson(ism). They might be related to cerebral small-vessel disease, although this association remains incompletely understood. To identify subjects at early stages of the disease, we investigated whether the presence of MPS was dependent on the severity and location of small-vessel disease, including white matter lesions and lacunar infarcts.

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