No Increased Risk of Symptomatic Intracerebral Hemorrhage After Thrombolysis in Patients With European Cooperative Acute Stroke Study (ECASS) Exclusion Criteria | Zendy

Carolyn Cronin | Zendy; Nikeith Shah | Zendy; Tanya Morovati | Zendy; Lisa Hermann | Zendy; Kevin N. Sheth | Zendy

Open Access

No Increased Risk of Symptomatic Intracerebral Hemorrhage After Thrombolysis in Patients With European Cooperative Acute Stroke Study (ECASS) Exclusion Criteria

Author(s) -

Carolyn Cronin,

Nikeith Shah,

Tanya Morovati,

Lisa Hermann,

Kevin N. Sheth

Publication year - 2012

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.112.656587

Subject(s) - medicine , intracerebral hemorrhage , thrombolysis , atrial fibrillation , stroke (engine) , diabetes mellitus , surgery , subarachnoid hemorrhage , myocardial infarction , endocrinology , mechanical engineering , engineering

The European Cooperative Acute Stroke Study (ECASS) III trial used additional exclusion criteria not present in current guidelines for thrombolytic therapy in the United States (age >80 years; National Institutes of Health Stroke Scale >25, combination of previous stroke and diabetes, aggressive measures required to control blood pressure [intravenous infusion], and oral anticoagulant treatment). We tested the hypothesis that thrombolysis is not safe in patients with 1 of the additional exclusion criteria.

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