Open AccessEffect of Addition of Clopidogrel to Aspirin on Mortality
Author(s) -
S. del Palacio,
Robert G. Hart,
Lesly A. Pearce,
Oscar Benavente
Publication year - 2012
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.112.656173
Subject(s) - medicine , clopidogrel , aspirin , stroke (engine) , cardiology , mechanical engineering , engineering
In the Secondary Prevention of Small Subcortical Strokes (SPS3) trial, addition of clopidogrel to aspirin was associated with an unexpected increase in mortality in patients with lacunar strokes. We assessed the effect of the addition of clopidogrel to aspirin on mortality in a meta-analysis of published randomized trials.
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