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Citicoline Enhances Neuroregenerative Processes After Experimental Stroke in Rats
Author(s) -
Kai Diederich,
Katrin Frauenknecht,
Jens Minnerup,
Barbara Schneider,
Antje Schmidt,
Elena Altach,
Verena Eggert,
Clemens Sommer,
WolfRüdiger Schäbitz
Publication year - 2012
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.112.654806
Subject(s) - citicoline , medicine , neurogenesis , neuroprotection , stroke (engine) , subventricular zone , neuroregeneration , ischemia , anesthesia , stroke recovery , neurology , neuroscience , pharmacology , neural stem cell , rehabilitation , physical therapy , stem cell , mechanical engineering , genetics , psychiatry , engineering , biology
The neuroprotective potential of citicoline in acute ischemic stroke has been shown in many experimental studies and, although the exact mechanisms are still unknown, a clinical Phase III trial is currently underway. Our present study was designed to check whether citicoline also enhances neuroregeneration after experimental stroke.

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