Near-Term Fetal Hypoxia–Ischemia in Rabbits | Zendy

Alexander Drobyshevsky | Zendy; Matthew Derrick | Zendy; Kehuan Luo | Zendy; Liqun Zhang | Zendy; YiNing Wu | Zendy; Silvia Honda Takada | Zendy; Lei Yu | Zendy; Sidhartha Tan | Zendy

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Near-Term Fetal Hypoxia–Ischemia in Rabbits

Author(s) -

Alexander Drobyshevsky,

Matthew Derrick,

Kehuan Luo,

Liqun Zhang,

YiNing Wu,

Silvia Honda Takada,

Lei Yu,

Sidhartha Tan

Publication year - 2012

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.112.653857

Subject(s) - medicine , hypertonia , ischemia , hypoxia (environmental) , anesthesia , periventricular leukomalacia , gestation , fetus , gestational age , pregnancy , chemistry , organic chemistry , biology , oxygen , genetics

The pattern of antenatal brain injury varies with gestational age at the time of insult. Deep brain nuclei are often injured at older gestational ages. Having previously shown postnatal hypertonia after preterm fetal rabbit hypoxia-ischemia, the objective of this study was to investigate the causal relationship between the dynamic regional pattern of brain injury on MRI and the evolution of muscle tone in the near-term rabbit fetus.

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