Patients With the Malignant Profile Within 3 Hours of Symptom Onset Have Very Poor Outcomes After Intravenous Tissue-Type Plasminogen Activator Therapy | Zendy

Manabu Inoue | Zendy; Michael Mlynash | Zendy; Matús Straka | Zendy; Maarten G. Lansberg | Zendy; Greg Zaharchuk | Zendy; Roland Bammer | Zendy; Gregory W. Albers | Zendy

Open Access

Patients With the Malignant Profile Within 3 Hours of Symptom Onset Have Very Poor Outcomes After Intravenous Tissue-Type Plasminogen Activator Therapy

Author(s) -

Manabu Inoue,

Michael Mlynash,

Matús Straka,

Maarten G. Lansberg,

Greg Zaharchuk,

Roland Bammer,

Gregory W. Albers

Publication year - 2012

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.112.653329

Subject(s) - medicine , modified rankin scale , interquartile range , perfusion , thrombolysis , perfusion scanning , tissue plasminogen activator , receiver operating characteristic , t plasminogen activator , stroke (engine) , radiology , surgery , nuclear medicine , ischemia , ischemic stroke , mechanical engineering , myocardial infarction , engineering

The malignant profile has been associated with poor outcomes after reperfusion in the 3- to 6-hour time window. The aim of this study was to estimate the incidence and prognostic implications of the malignant profile, as identified by CT perfusion, in intravenous tissue-type plasminogen activator-treated patients who were imaged <3 hours from stroke onset.

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