Stroke in Children With Posterior Fossa Brain Malformations, Hemangiomas, Arterial Anomalies, Coarctation of the Aorta and Cardiac Defects, and Eye Abnormalities (PHACE) Syndrome | Zendy

Dawn H. Siegel | Zendy; Kimberly A. Tefft | Zendy; Teresa Kelly | Zendy; Craig M. Johnson | Zendy; Denise W. Metry | Zendy; Patricia E. Burrows | Zendy; Elena Pope | Zendy; Maria Cordisco | Zendy; Kristen E. Holland | Zendy; Mohit Maheshwari | Zendy; Phillip Keith | Zendy; Maria C. Garzón | Zendy; Christopher P. Hess | Zendy; Ilona J. Frieden | Zendy; Heather J. Fullerton | Zendy; Beth A. Drolet | Zendy

Open Access

Stroke in Children With Posterior Fossa Brain Malformations, Hemangiomas, Arterial Anomalies, Coarctation of the Aorta and Cardiac Defects, and Eye Abnormalities (PHACE) Syndrome

Author(s) -

Dawn H. Siegel,

Kimberly A. Tefft,

Teresa Kelly,

Craig M. Johnson,

Denise W. Metry,

Patricia E. Burrows,

Elena Pope,

Maria Cordisco,

Kristen E. Holland,

Mohit Maheshwari,

Phillip Keith,

Maria C. Garzón,

Christopher P. Hess,

Ilona J. Frieden,

Heather J. Fullerton,

Beth A. Drolet

Publication year - 2012

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.112.650952

Subject(s) - medicine , coarctation of the aorta , hypoplasia , stroke (engine) , cardiology , aorta , aortic arch , angioma , radiology , vascular disease , mechanical engineering , engineering

PHACE is an acronym for posterior fossa brain malformations, hemangiomas, arterial anomalies, coarctation of the aorta and cardiac defects, and eye abnormalities. Several case reports of arterial ischemic stroke (AIS) in individuals with PHACE have been published, but risk factors for AIS in PHACE have not been clearly defined. The objective of this article is to review all cases of stroke in PHACE in children and describe clinical characteristics that may be associated with an increased risk of AIS.

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