Autonomic Blockade During Sinusoidal Baroreflex Activation Proves Sympathetic Modulation of Cerebral Blood Flow Velocity
Author(s) -
Max J. Hilz,
Julia Koehn,
A. Tillmann,
Stephan Riss,
H. Marthol,
Martin Köhrmann,
Gerald Wasmeier,
Stefan Schwab,
Brigitte Stemper
Publication year - 2013
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.111.680256
Subject(s) - medicine , baroreflex , cerebral blood flow , blockade , blood flow , anesthesia , cardiology , autonomic nervous system , sympathetic nervous system , blood pressure , heart rate , receptor
Pharmacological blockade showed sympathetic origin of 0.03 to 0.15 Hz blood pressure (BP) oscillations and parasympathetic origin of 0.15 to 0.5 Hz RR-interval (RRI) oscillations, but has not been used to determine origin of cerebral blood flow velocity (CBFV) oscillations at these frequencies. This study evaluated by pharmacological blockade whether 0.1 Hz CBFV oscillations are related to sympathetic and 0.2 Hz CBFV oscillations to parasympathetic modulation.
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