Anticoagulation for Cerebral Venous Sinus Thrombosis

Treatment of cerebral venous thrombosis with anticoagulants may prevent new venous infarcts, neurological deterioration, and pulmonary embolism but may also promote hemorrhages. ObjectivesThe objective of the study was to assess the efficacy and safety of anticoagulant therapy in patients with radiologically confirmed cerebral venous thrombosis. This is an update of the 2002 version of the Cochrane Review on this topic.1 Search StrategyWe searched the Cochrane Stroke Group Trials Register (last searched August 2010), MEDLINE (1950 to August 2010), EMBASE (1980 to August 2010), and the Cochrane Central Register of Controlled Trials (The Cochrane Library, 2011 Issue 1). In an effort to identify further published, unpublished, and ongoing trials, we searched ongoing trial registers and reference lists of relevant articles and contacted the authors. Selection CriteriaSelection criteria included nonconfounded randomized controlled trials in which anticoagulant …