Tissue Factor Pathway Inhibitor, Activated Protein C Resistance, and Risk of Ischemic Stroke due to Postmenopausal Hormone Therapy
Author(s) -
Jacques E. Rossouw,
Karen Johnson,
Mary Pettinger,
Mary Cushman,
Per Morten Sandset,
Lewis H. Kuller,
Frits R. Rosendaal,
Jan Rosing,
Sylvia Wasserthal-Smoller,
Lisa W. Martin,
JoAnn E. Manson,
Kamakshi Lakshminarayan,
José G. Merino,
J.A. Lynch
Publication year - 2012
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.111.643072
Subject(s) - medicine , hormone therapy , stroke (engine) , tissue factor pathway inhibitor , activated protein c resistance , risk factor , ischemic stroke , endocrinology , gastroenterology , tissue factor , ischemia , breast cancer , thrombosis , cancer , mechanical engineering , factor v leiden , venous thrombosis , engineering , coagulation
To test whether changes in plasma tissue factor pathway inhibitor (TFPI) levels or activated protein C resistance (normalized activated protein C resistance ratio [nAPCsr]) modify the increased risk of ischemic stroke due to postmenopausal hormone therapy.
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