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Critique of “Stenting Versus Aggressive Medical Therapy for Intracranial Arterial Stenosis” by Chimowitz et al in the New England Journal of Medicine
Author(s) -
Alex AbouChebl,
Helmuth Steinmetz
Publication year - 2012
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.111.641563
Subject(s) - medicine , medical therapy , stroke (engine) , stenosis , cardiology , radiology , surgery , mechanical engineering , engineering
Symptomatic intracranial stenoses are an important cause of stroke and have a high risk of recurrent stroke with medical therapy. The Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Arterial Stenosis (SAMMPRIS) trial unexpectedly showed a higher-than-expected rate of complications with intracranial stenting and a lower-than-expected recurrence rate with medical therapy. In this commentary, the authors review possible explanations for these findings and suggest future strategies for study.

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