Insulin for Glycemic Control in Acute Ischemic Stroke | Zendy

Fernanda Bellolio | Zendy; R.M. Gilmore | Zendy; Latha Ganti | Zendy

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Insulin for Glycemic Control in Acute Ischemic Stroke

Author(s) -

Fernanda Bellolio,

R.M. Gilmore,

Latha Ganti

Publication year - 2012

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.111.637769

Subject(s) - medicine , emergency department , glycemic , stroke (engine) , acute stroke , emergency medicine , insulin , nursing , mechanical engineering , engineering

Hyperglycemia predicts increased stroke mortality independently of age, stroke severity, or stroke type. The next step is to ascertain whether treating hyperglycemia reduces mortality and improves functional outcome.The objective of this review was to determine whether maintaining serum glucose within a specific normal range (4–7.5 mmol/L or 72–135 mg/dL) in the first 24 hours of acute ischemic stroke influences outcome.We searched the Cochrane Stroke Group Trials Register, CENTRAL, MEDLINE, EMBASE, CINAHL, Science Citation Index, Web of Science, ongoing trials registers, and SCOPUS. Eligible studies were randomized controlled trials comparing intensively monitored insulin therapy versus usual care in adult patients with acute ischemic stroke.We obtained a total of 191 …

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