Granulocyte-Colony Stimulating Factor for Mobilizing Bone Marrow Stem Cells in Subacute Stroke | Zendy

Timothy J. England | Zendy; Maryam Abaei | Zendy; Dorothee P. Auer | Zendy; James Lowe | Zendy; David Jones | Zendy; Gillian M. Sare | Zendy; Marion Walker | Zendy; Philip M. Bath | Zendy

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Granulocyte-Colony Stimulating Factor for Mobilizing Bone Marrow Stem Cells in Subacute Stroke

Author(s) -

Timothy J. England,

Maryam Abaei,

Dorothee P. Auer,

James Lowe,

David Jones,

Gillian M. Sare,

Marion Walker,

Philip M. Bath

Publication year - 2011

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.111.636449

Subject(s) - medicine , granulocyte colony stimulating factor , placebo , stroke (engine) , modified rankin scale , cd34 , bone marrow , gastroenterology , lesion , adverse effect , surgery , stem cell , pathology , chemotherapy , ischemia , ischemic stroke , mechanical engineering , alternative medicine , biology , engineering , genetics

Granulocyte-colony stimulating factor (G-CSF) is neuroprotective in experimental stroke and mobilizes CD34(+) peripheral blood stem cells into the circulation. We assessed the safety of G-CSF in recent stroke in a phase IIb single-center randomized, controlled trial.

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