Fibrin D-Dimer, Tissue-Type Plasminogen Activator, von Willebrand Factor, and Risk of Incident Stroke in Older Men | Zendy

S. Goya Wannamethee | Zendy; Peter H. Whincup | Zendy; Lucy Len | Zendy; Ann Rumley | Zendy; Gordon Lowe | Zendy

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Fibrin D-Dimer, Tissue-Type Plasminogen Activator, von Willebrand Factor, and Risk of Incident Stroke in Older Men

Author(s) -

S. Goya Wannamethee,

Peter H. Whincup,

Lucy Len,

Ann Rumley,

Gordon Lowe

Publication year - 2012

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.111.636373

Subject(s) - medicine , stroke (engine) , von willebrand factor , d dimer , hazard ratio , fibrinogen , tissue plasminogen activator , confidence interval , prospective cohort study , risk factor , odds ratio , fibrin , cardiology , gastroenterology , immunology , platelet , mechanical engineering , engineering

Abnormalities in blood coagulation and the fibrinolytic system have been associated with increased risk of stroke, but few prospective studies have studied the associations in older adults. We have examined the associations between fibrin D-dimer, tissue-type plasminogen activator, and von Willebrand factor (vWF) and risk of stroke in older men and examined their predictive roles separately in normotensive and hypertensive men.

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