The Safety of Intravenous Thrombolysis for Ischemic Stroke in Patients With Pre-Existing Cerebral Aneurysms | Zendy

Nancy Edwards | Zendy; Hooman Kamel | Zendy; S. Andrew Josephson | Zendy

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The Safety of Intravenous Thrombolysis for Ischemic Stroke in Patients With Pre-Existing Cerebral Aneurysms

Author(s) -

Nancy Edwards,

Hooman Kamel,

S. Andrew Josephson

Publication year - 2011

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.111.634147

Subject(s) - medicine , subarachnoid hemorrhage , contraindication , thrombolysis , aneurysm , surgery , stroke (engine) , pathology , myocardial infarction , mechanical engineering , alternative medicine , engineering

Unruptured cerebral aneurysms are currently considered a contraindication to intravenous tissue-type plasminogen activator for acute ischemic stroke. This is due to a theoretical increase in the risk of hemorrhage from aneurysm rupture, although it is unknown whether this risk is a significant one. We sought to determine the safety of intravenous tissue-type plasminogen activator administration in a cohort of patients with pre-existing aneurysms.

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