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Low-Dose Intravenous Recombinant Tissue-Type Plasminogen Activator Therapy for Patients With Stroke Outside European Indications
Author(s) -
Masatoshi Koga,
Yoshiaki Shiokawa,
Jyoji Nakagawara,
Eisuke Furui,
Kazumi Kimura,
Hiroshi Yamagami,
Yasushi Okada,
Yasuhiro Hasegawa,
Kazuomi Kario,
Satoshi Okuda,
Kaoru Endô,
Tetsuya Miyagi,
Masato Osaki,
Kazuo Minematsu,
Ḱazunori Toyoda
Publication year - 2011
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.111.631176
Subject(s) - medicine , intracerebral hemorrhage , plasminogen activator , recombinant dna , stroke (engine) , tissue plasminogen activator , surgery , t plasminogen activator , gastroenterology , subarachnoid hemorrhage , mechanical engineering , biochemistry , chemistry , engineering , gene
The purpose of this study was to determine the safety and efficacy of intravenous recombinant tissue-type plasminogen activator (0.6 mg/kg alteplase) within 3 hours of stroke onset in Japanese patients outside the indications in the European license.

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