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Neuroprotective Effect of Acute Ethanol Administration in a Rat With Transient Cerebral Ischemia
Author(s) -
Fei Wang,
Yu Wang,
Xiaokun Geng,
Karam Asmaro,
Changya Peng,
Jonathon M. Sullivan,
Jamie Y. Ding,
Xunming Ji,
Yuchuan Ding
Publication year - 2011
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.111.629576
Subject(s) - neuroprotection , medicine , ischemia , hypothermia , intracerebral hemorrhage , anesthesia , stroke (engine) , hypoxia (environmental) , middle cerebral artery , ethanol , tissue plasminogen activator , pharmacology , infarction , plasminogen activator , brain ischemia , cerebral infarction , subarachnoid hemorrhage , biochemistry , myocardial infarction , mechanical engineering , chemistry , organic chemistry , oxygen , engineering
Ethanol consumption is inversely associated with the risk of ischemic stroke, suggesting a neuroprotective effect. In a rat model of transient cerebral ischemia, we identified ethanol as a possible treatment for acute ischemic stroke.

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