Recombinant Activated Coagulation Factor VII and Prothrombin Complex Concentrates Are Equally Effective in Reducing Hematoma Volume in Experimental Warfarin-Associated Intracerebral Hemorrhage | Zendy

Frieder Schlunk | Zendy; Elizabeth M. Van Cott | Zendy; Kazuhide Hayakawa | Zendy; Waltraud Pfeilschifter | Zendy; Eng H. Lo | Zendy; Christian Foerch | Zendy

Open Access

Recombinant Activated Coagulation Factor VII and Prothrombin Complex Concentrates Are Equally Effective in Reducing Hematoma Volume in Experimental Warfarin-Associated Intracerebral Hemorrhage

Author(s) -

Frieder Schlunk,

Elizabeth M. Van Cott,

Kazuhide Hayakawa,

Waltraud Pfeilschifter,

Eng H. Lo,

Christian Foerch

Publication year - 2011

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.111.629360

Subject(s) - medicine , intracerebral hemorrhage , prothrombin complex concentrate , warfarin , saline , anesthesia , hematoma , coagulation , prothrombin time , recombinant factor viia , factor vii , stroke (engine) , surgery , mechanical engineering , subarachnoid hemorrhage , engineering , atrial fibrillation

Based on an experimental model of warfarin-associated intracerebral hemorrhage, we investigated whether the rapid reversal of anticoagulation using prothrombin complex concentrates (PCC) or recombinant activated coagulation factor VII (rFVIIa) reduces hematoma volume.

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