Therapeutic Modulation of Cerebral Microhemorrhage in a Mouse Model of Cerebral Amyloid Angiopathy
Author(s) -
Mark Fisher,
Vitaly Vasilevko,
Giselle F. Passos,
Christopher Ventura,
Daniel P. Quiring,
David H. Cribbs
Publication year - 2011
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.111.626655
Subject(s) - cerebral amyloid angiopathy , medicine , dipyridamole , stroke (engine) , immunotherapy , amyloid (mycology) , cerebral infarction , pathology , dementia , ischemia , immunology , immune system , disease , mechanical engineering , engineering
The aging brain demonstrates frequent MRI and pathological evidence of cerebral microbleeds, which are often associated with cerebral amyloid angiopathy. To develop new therapeutic strategies for this disorder, we studied cerebral microhemorrhage in a well-characterized mouse model of cerebral amyloid angiopathy.
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